SCHEMBL666863

SCHEMBL666863

O=C(O)CC(O)COc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.57
ADRB2 P07550 2/20 0.57
ADRB1 P08588 2/20 0.57
ADRB3 P13945 2/20 0.57
LMNA P02545 2/20 0.55
ALOX15 P16050 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP1A2 P05177 1/20 0.52
KDM4E B2RXH2 1/20 0.51
MAPT P10636 3/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RECQL P46063 1/20 0.50
MMP12 P39900 2/20 0.49
MMP13 P45452 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4744800 1.00 CYP2D6 (0.57) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL4560021 0.91 CYP2D6 (0.53) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL4394718 0.84 FFAR1 (0.49) LMNAMAPTTSHRSMN1; SMN2
SCHEMBL7611725 0.84 ALDH1A1 (0.59) LMNAKDM4EMAPTTSHRHTT
SCHEMBL267463 0.83 LMNA (0.68) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL3673166 0.82 CYP2D6 (0.55) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL27526634 0.82 LMNA (0.49) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL183191 0.82 LMNA (0.49) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL3673164 0.82 CYP2D6 (0.55) CYP2D6ADRB2ADRB1ADRB3LMNA
SCHEMBL4653976 0.82 USP2 (0.51) ADRB2ADRB1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957533-B2 Mutant of propionyl-CoA transferase from Clostridium propionicum and preparing method for PLA or PLA copolymer using the same LG CHEM, LTD. (KR) 2018-05-01 US claimed
US-9920338-B2 Recombinant Ralstonia eutropha capable of producing polylactic acid or polylatic acid polymer, and method for producing polylactic acid or polylatic acid copolymer using same LG CHEM, LTD. (KR) 2018-03-20 US claimed
EP-2089522-B1 MUTANTS OF PHA SYNTHASE FROM PSEUDOMONAS SP.6-19 AND METHOD FOR PREPARING LACTATE HOMOPOLYMER OR COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2017-11-01 EP claimed
EP-2650372-B1 Preparation method of lactate polymers and lactate copolymers using polyhydroxyalkanoate synthase mutants LG CHEMICAL LTD (KR) 2017-03-01 EP claimed
US-20160312251-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2016-10-27 US claimed
US-9410167-B2 Cells or plants producing polylactate or its copolymers and uses thereof LG CHEM, LTD. (KR) 2016-08-09 US claimed
US-20160177348-A1 RECOMINANT RALSTONIA EUTROPHA CAPABLE OF PRODUCING POLYLACTIC ACID OR POLYLATIC ACID POLYMER, AND METHOD FOR PRODUCING POLYLACTIC ACID OR POLYLATIC ACID COPOLYMER USING SAME LG CHEM, LTD. (KR) 2016-06-23 US claimed
US-9243265-B2 Recominant Ralstonia eutropha capable of producing polyactic and acid or polylatic acid polymer, and method for producing polyactic acid or polylatic acid copolymer using the same LG CHEM, LTD. (KR) 2016-01-26 US claimed
EP-2636744-B1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEMICAL LTD (KR) 2015-04-08 EP claimed
US-20150031098-A1 MUTANT OF PROPIONYL-COA TRANSFERASE FROM CLOSTRIDIUM PROPIONICUM AND PREPARING METHOD FOR PLA OR PLA COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2015-01-29 US claimed
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP claimed
WO-2006126796-A1 CELLS OR PLANTS HAVING A PRODUCING ABILITY OF POLYLACTATE OR ITS COPOLYMERS AND METHOD FOR PREPARING POLYLACTATE OR ITS COPOLYMERS USING THE SAME LG CHEM, LTD. (KR) 2006-11-30 WO claimed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US claimed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US claimed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed