SCHEMBL4394718

SCHEMBL4394718

O=C(O)CC(O)COc1ccc(F)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.49
POLB P06746 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 1/20 0.47
NPC1 O15118 1/20 0.47
ABCB1 P08183 4/20 0.46
NR4A2 P43354 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CACNA1G O43497 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666863 0.84 CYP2D6 (0.57) MAPTLMNATSHRSMN1; SMN2
SCHEMBL4744800 0.84 CYP2D6 (0.57) MAPTLMNATSHRSMN1; SMN2
SCHEMBL4403318 0.83 MMP12 (0.47) FFAR1POLBNR4A2SMN1; SMN2
SCHEMBL7611725 0.83 ALDH1A1 (0.59) FFAR1POLBMAPTLMNANPSR1
SCHEMBL7234199 0.81 TBXA2R (0.48) POLBMAPTLMNANPSR1MEN1
SCHEMBL7178491 0.81 FFAR1 (0.48) FFAR1POLBMAPTLMNANPSR1
SCHEMBL4653976 0.81 USP2 (0.51) FFAR1MEN1KMT2ATSHRABCB1
SCHEMBL7234206 0.81 TBXA2R (0.48) POLBMAPTLMNANPSR1MEN1
Hydrochloric Acid SCHEMBL18939596 0.80 LTA4H (0.47) FFAR1POLBLMNANR4A2SMN1; SMN2
SCHEMBL667010 0.80 ALDH1A1 (0.55) POLBMAPTLMNANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
EP-1255166-B1 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KK (JP) 2009-12-16 EP disclosed
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
CN-1260266-C Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2006-06-21 CN disclosed
US-6858367-B2 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2005-02-22 US disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20030072594-A1 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2003-04-17 US disclosed
EP-1255166-A2 Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner CANON KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed