Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662134 | 0.89 | P2RX7 (0.33) | P2RX7HCRTR1HCRTR2PDE2AKCNH2 | |
| SCHEMBL6662858 | 0.88 | P2RX7 (0.33) | P2RX7HCRTR1HCRTR2PDE2AKCNH2 | |
| SCHEMBL6661657 | 0.87 | KDM1A (0.34) | KCNH2 | |
| SCHEMBL6666723 | 0.85 | HTR2C (0.34) | — | |
| SCHEMBL6664872 | 0.84 | GRM2 (0.33) | KCNH2 | |
| SCHEMBL6661199 | 0.84 | FFAR4 (0.33) | — | |
| SCHEMBL6663132 | 0.84 | ALDH1A1 (0.38) | P2RX7HCRTR1HCRTR2PDE2AKCNH2 | |
| SCHEMBL6665743 | 0.83 | RORC (0.33) | KCNH2 | |
| SCHEMBL6666418 | 0.82 | P2RX7 (0.32) | P2RX7HCRTR1HCRTR2PDE2AKCNH2 | |
| SCHEMBL6667749 | 0.82 | HTR2C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |