Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666113 | 0.86 | RAB9A (0.47) | RAB9AKMT2AMEN1GAAMAPT | |
| SCHEMBL6668749 | 0.84 | NR1H4 (0.36) | GAAMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6694399 | 0.78 | MAPT (0.41) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7477339 | 0.74 | NR1H4 (0.35) | GAANPC1ALDH1A1TP53KDM4E | |
| SCHEMBL6669484 | 0.74 | MAPK1 (0.36) | KMT2AMEN1GAAABCB1TP53 | |
| SCHEMBL6672672 | 0.74 | NR1H4 (0.34) | NPC1SMN1; SMN2 | |
| SCHEMBL6672237 | 0.72 | NR1H4 (0.33) | KMT2AMEN1 | |
| SCHEMBL6667472 | 0.72 | MEN1 (0.41) | RAB9AKMT2AMEN1GAAMAPT | |
| SCHEMBL6666111 | 0.72 | NR1H4 (0.37) | GAANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6668160 | 0.69 | KMT2A (0.49) | KMT2AMEN1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |