Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667470 | 0.84 | INSR (0.39) | RAB9AINSRIGF1RALKKCNH2 | |
| SCHEMBL6667762 | 0.83 | MEN1 (0.42) | MEN1GAARAB9AKMT2AKDM4E | |
| SCHEMBL6667777 | 0.82 | RAB9A (0.55) | MEN1GAARAB9AKMT2AKDM4E | |
| SCHEMBL6666561 | 0.80 | MAPT (0.39) | MEN1GAARAB9AKMT2AKDM4E | |
| SCHEMBL6669289 | 0.79 | NPC1 (0.40) | MEN1GAARAB9AKMT2AKDM4E | |
| SCHEMBL6695646 | 0.78 | POLA1 (0.54) | MEN1KMT2AKCNH2POLA1ENPP2 | |
| SCHEMBL6974853 | 0.77 | KCNH2 (0.47) | RAB9AKCNH2POLA1ENPP2GSK3B | |
| SCHEMBL6666496 | 0.76 | BACE1 (0.38) | MEN1GAARAB9AKMT2AKDM4E | |
| SCHEMBL6980565 | 0.74 | KCNH2 (0.44) | KCNH2POLA1ENPP2 | |
| SCHEMBL6666113 | 0.74 | RAB9A (0.47) | MEN1GAARAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |