Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141661 | 0.80 | GABRR1 (0.48) | GABRR1MAPTLMNACYP2D6CYP1A2 | |
| SCHEMBL9033183 | 0.77 | KMT2A (0.34) | CA1CA2MAPTCHRM2CHRM4 | |
| SCHEMBL7508980 | 0.77 | CHRNB2 (0.36) | CA1CA2GABRR1MAPTCYP1A2 | |
| SCHEMBL23771146 | 0.77 | CA12 (0.35) | NPSR1CA1CA2MAPTLMNA | |
| SCHEMBL23771151 | 0.77 | MAPT (0.34) | MAPTLMNACYP2D6CYP1A2SLC22A1 | |
| SCHEMBL27847066 | 0.76 | MEN1 (0.37) | CA1CA2GABRR1TSHRSLC22A2 | |
| Hydrochloric Acid SCHEMBL21197508 | 0.76 | CHRNB2 (0.35) | CA1CA2GABRR1MAPTLMNA | |
| SCHEMBL10469243 | 0.75 | SLC22A1 (0.38) | NPSR1CA1CA2MAPTLMNA | |
| SCHEMBL18125221 | 0.74 | — | — | |
| Isobutyramide SCHEMBL22164865 | 0.74 | ALOX15 (0.37) | NPSR1CA1CA2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878801-A | Water-soluble copolymers of monoethylenically unsaturated polyalkylene oxide monomers and dipolar monomers containing at least one nitrogen atom | BASF AG (DE) | 2006-12-13 | — | — | CN | disclosed |
| EP-1487841-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | Abbott Laboratories (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080625-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-10-02 | — | — | WO | disclosed |