Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13559804 | 0.79 | CHRNB2 (0.31) | CA1CA2EPHX1 | |
| SCHEMBL28546524 | 0.78 | CHRM2 (0.38) | KMT2AHTTMEN1GAACA1 | |
| SCHEMBL103178 | 0.78 | GABRR1 (0.41) | KMT2AHTTMEN1GAASCN1A | |
| SCHEMBL5538685 | 0.78 | GABRR1 (0.41) | KMT2AHTTMEN1GAASCN1A | |
| SCHEMBL21787595 | 0.77 | KDM4E (0.33) | CA1CA2CA12CA9MAPT | |
| SCHEMBL6668916 | 0.77 | NPSR1 (0.35) | GAACA1CA2CHRM2CHRM4 | |
| Isobutyramide SCHEMBL22164865 | 0.77 | ALOX15 (0.37) | HTTCA1CA2CHRM2CHRM4 | |
| SCHEMBL19532380 | 0.76 | L3MBTL1 (0.36) | KMT2AHTTMEN1GAACA1 | |
| SCHEMBL28601448 | 0.76 | PLA2G1B (0.38) | KMT2AHTTMEN1GAACA1 | |
| SCHEMBL4489176 | 0.76 | L3MBTL1 (0.36) | KMT2AHTTMEN1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959191-A | Novel hydrophobic polyurethane foams | W. R. GRACE & CO. (US) | 1976-05-25 | — | — | US | claimed |
| EP-0429344-B1 | Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1996-09-18 | — | — | EP | disclosed |
| EP-0429344-A1 | Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1991-05-29 | — | — | EP | disclosed |
| US-3959191-A | Novel hydrophobic polyurethane foams | W. R. GRACE & CO. (US) | 1976-05-25 | — | — | US | disclosed |