Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645111 | 0.74 | MAPT (0.46) | RAB9ANPC1ATMRXFP1KLK7 | |
| SCHEMBL5166401 | 0.71 | KLK7 (0.40) | RAB9ANPC1ATMRXFP1KLK7 | |
| SCHEMBL5165831 | 0.69 | KDM4E (0.47) | RAB9ANPC1ATMRXFP1KLK7 | |
| SCHEMBL6671073 | 0.69 | ALDH1A1 (0.37) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL5167498 | 0.69 | KLK7 (0.44) | RAB9ANPC1ATMRXFP1KLK7 | |
| SCHEMBL5167506 | 0.67 | KLK7 (0.40) | RAB9ANPC1ATMRXFP1KLK7 | |
| SCHEMBL5169013 | 0.64 | ALOX5 (0.43) | RAB9ANPC1ATMRXFP1KDM4E | |
| Hydrochloric Acid SCHEMBL5166777 | 0.64 | ALOX5 (0.42) | RAB9ANPC1ATMRXFP1KDM4E | |
| Hydrochloric Acid SCHEMBL5166037 | 0.64 | LMNA (0.45) | RAB9ANPC1ATMKDM4EALDH1A1 | |
| SCHEMBL5164712 | 0.63 | MAPT (0.44) | RAB9ANPC1ATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218382-B1 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-01-28 | — | — | EP | claimed |