Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665701 | 0.87 | ALDH1A1 (0.36) | ALDH1A1FPR1MEN1KMT2AHPGD | |
| SCHEMBL6665519 | 0.86 | ALDH1A1 (0.39) | ALDH1A1FPR1MEN1KMT2AHPGD | |
| SCHEMBL5843030 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL6610297 | 0.82 | MAPT (0.53) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL6615771 | 0.80 | ALDH1A1 (0.42) | SLC2A1ALDH1A1TGM2MEN1KMT2A | |
| SCHEMBL6613130 | 0.79 | SLC2A1 (0.39) | SLC2A1ALDH1A1TGM2MEN1KMT2A | |
| SCHEMBL6609671 | 0.78 | BCHE (0.47) | SLC2A1ALDH1A1TGM2MEN1KMT2A | |
| SCHEMBL6610777 | 0.77 | POLB (0.42) | SLC2A1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6611945 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL6611127 | 0.75 | NPSR1 (0.49) | SLC2A1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |