SCHEMBL6669183

SCHEMBL6669183

NCC(=O)OC1=CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.36
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CTSK P43235 1/20 0.33
ALDH1A1 P00352 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760986 0.98 GSTP1 (0.35) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL9390766 0.94 HDAC3 (0.33) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL3775177 0.85 GSTP1 (0.37) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL7566848 0.83 GSTP1 (0.36) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL11520789 0.82 GAA (0.38) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL3364604 0.81 GSTP1 (0.36) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL1695435 0.81 ESR1 (0.41) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL10736533 0.81 ALDH1A1 (0.40) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL4049811 0.81 KMT2A (0.36) GSTP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL1695482 0.80 ESR1 (0.40) GSTP1HDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004020649-A1 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAMS BIOFERMA MURCIA, S.A. (ES) 2004-03-11 WO disclosed
US-3937699-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-02-10 US disclosed