SCHEMBL6669749

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6671608	1.00	TOP1 (0.46)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL6647359	0.94	ALDH1A1 (0.42)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL6670392	0.87	KCNH2 (0.43)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL6649151	0.87	KCNH2 (0.59)	TOP1KCNH2
	SCHEMBL6670298	0.87	KCNH2 (0.43)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL7097216	0.87	KCNH2 (0.43)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL6670700	0.87	KCNH2 (0.47)	KCNH2ALDH1A1POLBOPRM1CHRM2
	SCHEMBL6670694	0.87	KCNH2 (0.47)	KCNH2ALDH1A1POLBOPRM1CHRM2
	SCHEMBL7092967	0.86	KCNH2 (0.42)	TOP1KCNH2ALDH1A1POLBOPRM1
	SCHEMBL6669998	0.85	KCNH2 (0.51)	TOP1KCNH2ALDH1A1POLBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.