Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 5/20 | 0.47 |
| ▸ | GABRD | O14764 | 5/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.47 |
| ▸ | GABRE | P78334 | 5/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669904 | 0.94 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7847448 | 0.87 | GABRA1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6671873 | 0.86 | TP53 (0.48) | GABRA1GABRB2TP53MAPTGAA | |
| SCHEMBL6670716 | 0.79 | TP53 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6669810 | 0.75 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7834064 | 0.74 | GAA (0.51) | GABRA1GABRB2TP53MAPTGAA | |
| SCHEMBL7845846 | 0.74 | GAA (0.51) | GABRA1GABRB2TP53MAPTGAA | |
| SCHEMBL7834337 | 0.72 | KDM4E (0.49) | GABRA1GABRB1GABRA3GABRB2TP53 | |
| SCHEMBL7834749 | 0.70 | GAA (0.48) | GABRA1GABRB2TP53MAPTGAA | |
| SCHEMBL7843694 | 0.70 | GAA (0.46) | GABRA1GABRB2TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |