Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.49 |
| ▸ | GABRD | O14764 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.49 |
| ▸ | GABRE | P78334 | 3/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671877 | 0.86 | POLB (0.50) | POLBLMNAMAPTTDP1NHERF1 | |
| SCHEMBL7847448 | 0.81 | GABRA1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6670721 | 0.79 | NHERF1 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6695944 | 0.77 | KCNH2 (0.54) | MAPT | |
| SCHEMBL6669904 | 0.76 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6669804 | 0.75 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7834823 | 0.74 | NHERF1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6609485 | 0.73 | POLA1 (0.68) | — | |
| SCHEMBL7842334 | 0.72 | NHERF1 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7845633 | 0.70 | NHERF1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |