Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17186982 | 0.79 | HTR2C (0.35) | MAPTKMT2AMEN1HTR2AHTR2C | |
| SCHEMBL1099044 | 0.77 | KMT2A (0.41) | MAPTKMT2AFGFR1CHEK1LIMK1 | |
| SCHEMBL1831523 | 0.74 | ALDH1A1 (0.42) | MAPTKMT2ATDP1MEN1HTT | |
| SCHEMBL8775921 | 0.74 | MAPT (0.45) | MAPTTHRBKMT2ATDP1FABP4 | |
| SCHEMBL11430315 | 0.72 | MAPT (0.39) | MAPTKMT2ATDP1FGFR1CHEK1 | |
| SCHEMBL3987798 | 0.68 | MAPT (0.43) | MAPTTHRBKMT2ATDP1FABP4 | |
| SCHEMBL3713957 | 0.67 | KCNMA1 (0.39) | KMT2ABACE1 | |
| SCHEMBL20665086 | 0.67 | HCAR3 (0.58) | MAPTTHRBKMT2AFGFR1FABP4 | |
| SCHEMBL13677265 | 0.66 | BACE1 (0.44) | MAPTTHRBKMT2ATDP1BACE1 | |
| SCHEMBL13676924 | 0.66 | MAPT (0.41) | MAPTTHRBKMT2ATDP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141021-B1 | REMOVAL/PURIFICATION OF SERUM ALBUMINS | AMERSHAM BIOSCIENCES AB (SE) | 2004-09-08 | — | — | EP | disclosed |