SCHEMBL6670093

SCHEMBL6670093

Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1COC(=O)c1ccccc1C(=O)OCc1c(C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.53
TSHR P16473 8/20 0.46
ALDH1A1 P00352 8/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL790678 0.71 HTR1D (0.39) TDP1TSHRLMNAMAPK1TP53
SCHEMBL11769547 0.70 CYP2C19 (0.43) TDP1TSHRALDH1A1LMNACYP3A4
SCHEMBL7574017 0.70 HTR1D (0.41) TDP1TSHRLMNACYP3A4MAPK1
SCHEMBL11766637 0.69 TDP1 (0.42) TDP1TSHRALDH1A1LMNACYP3A4
SCHEMBL1787314 0.69 TSHR (0.69) TDP1TSHRALDH1A1LMNAL3MBTL1
SCHEMBL28557792 0.69 CYP2C19 (0.39) TDP1TSHRALDH1A1LMNACYP3A4
SCHEMBL6668865 0.68 HTR1D (0.48) TSHRALDH1A1LMNACYP3A4MAPK1
SCHEMBL10692624 0.68 HTT (0.47) LMNAMAPTKMT2A
SCHEMBL4412838 0.68 HTR1D (0.52) TDP1TSHRALDH1A1LMNACYP3A4
SCHEMBL6667803 0.67 TSHR (0.46) TDP1TSHRALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed