Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | PGK2 | P07205 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.34 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789566 | 0.85 | HTR1D (0.40) | HTR1DHTR1BTDP1HMGCRLMNA | |
| SCHEMBL7574017 | 0.78 | HTR1D (0.41) | HTR1DHTR1BTDP1LMNAGABRA1 | |
| SCHEMBL4278881 | 0.76 | HMGCR (0.48) | HMGCRLMNANR5A2NR5A1GABRA1 | |
| SCHEMBL27943472 | 0.76 | HMGCR (0.48) | HMGCRLMNANR5A2NR5A1GABRA1 | |
| SCHEMBL603636 | 0.75 | ALDH1A1 (0.36) | HMGCRPGK1PGK2NR5A2NR5A1 | |
| SCHEMBL28428492 | 0.72 | SRC (0.49) | HTR1DHTR1BHMGCRPGK1PGK2 | |
| SCHEMBL6668865 | 0.72 | HTR1D (0.48) | HTR1DHTR1BLMNAGABRA1GABRB2 | |
| SCHEMBL4412838 | 0.72 | HTR1D (0.52) | HTR1DHTR1BTDP1LMNAGABRA1 | |
| SCHEMBL6670093 | 0.71 | TDP1 (0.53) | TDP1LMNATP53TSHRMAPK1 | |
| SCHEMBL26876706 | 0.70 | HTR1D (0.55) | HTR1DHTR1BTDP1LMNANR5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616473-B1 | MIXTURES CONTAINING PHOSPHOROUS, PROCEDURES FOR THEIR PRODUCTION AND USE | CLARIANT INT LTD (CH) | 2016-11-09 | — | — | EP | disclosed |
| EP-2616473-A2 | PHOSPHORUS-CONTAINING MIXTURES, PROCESSES FOR PREPARING THEM AND USE THEREOF | Clariant Finance (BV) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034680-A2 | PHOSPHORUS-CONTAINING MIXTURES, PROCESSES FOR PREPARING THEM AND USE THEREOF | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |