Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.42 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668180 | 0.81 | TSHR (0.49) | TSHRKDM4EKCNH2POLA1MAPT | |
| SCHEMBL6974853 | 0.79 | KCNH2 (0.47) | TSHRKCNH2POLA1ENPP2 | |
| SCHEMBL6670571 | 0.78 | KDM4E (0.39) | TSHRKDM4EKCNH2HIF1AEPAS1 | |
| SCHEMBL6980565 | 0.77 | KCNH2 (0.44) | KCNH2POLA1ENPP2 | |
| SCHEMBL6667762 | 0.76 | MEN1 (0.42) | KDM4EKCNH2POLA1MAPT | |
| SCHEMBL6695789 | 0.73 | POLA1 (0.54) | TSHRKCNH2POLA1ABCB1ENPP2 | |
| SCHEMBL6690162 | 0.73 | POLA1 (0.54) | TSHRKCNH2POLA1ABCB1ENPP2 | |
| SCHEMBL6699742 | 0.72 | POLA1 (0.59) | TSHRKCNH2POLA1ABCB1 | |
| SCHEMBL6697394 | 0.71 | POLA1 (0.59) | TSHRKCNH2POLA1ABCB1 | |
| SCHEMBL6694375 | 0.71 | KCNH2 (0.57) | TSHRKCNH2POLA1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |