Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.36 |
| ▸ | CTRL | P40313 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667470 | 0.81 | INSR (0.39) | ENPP2KCNH2 | |
| SCHEMBL6670577 | 0.78 | TSHR (0.47) | KDM4EENPP2KCNH2TSHRHIF1A | |
| SCHEMBL6668180 | 0.77 | TSHR (0.49) | KDM4EENPP2KCNH2TSHRHIF1A | |
| SCHEMBL6667754 | 0.77 | AKR1C3 (0.39) | ENPP2KCNH2PDE1B | |
| SCHEMBL6667774 | 0.76 | CHEK1 (0.46) | KDM4EKCNH2PDE1BJAK2 | |
| SCHEMBL7472513 | 0.76 | AKR1C3 (0.36) | ENPP2KCNH2SMN1; SMN2PDE1B | |
| SCHEMBL7007040 | 0.76 | PDE1B (0.45) | ENPP2KCNH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL7478855 | 0.75 | POLA1 (0.39) | ENPP2KCNH2PDE1B | |
| SCHEMBL6669285 | 0.74 | POLA1 (0.35) | KDM4EENPP2KCNH2SMN1; SMN2 | |
| SCHEMBL7475511 | 0.72 | NR1H4 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |