Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.47 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980565 | 0.92 | KCNH2 (0.44) | KCNH2POLA1ALDH1A1ENPP2 | |
| SCHEMBL6694266 | 0.85 | POLA1 (0.54) | KCNH2POLA1ALDH1A1TSHRENPP2 | |
| SCHEMBL6667762 | 0.83 | MEN1 (0.42) | KCNH2POLA1ALDH1A1RAB9A | |
| SCHEMBL6692334 | 0.81 | POLA1 (0.52) | KCNH2POLA1ALDH1A1TSHRENPP2 | |
| SCHEMBL6670577 | 0.79 | TSHR (0.47) | KCNH2POLA1TSHRENPP2 | |
| SCHEMBL6699742 | 0.79 | POLA1 (0.59) | KCNH2POLA1ALDH1A1NPC1RAB9A | |
| SCHEMBL6693414 | 0.77 | POLA1 (0.51) | KCNH2POLA1ALDH1A1TSHRENPP2 | |
| SCHEMBL6667472 | 0.77 | MEN1 (0.41) | KCNH2POLA1RAB9AGSK3BENPP2 | |
| SCHEMBL6697394 | 0.76 | POLA1 (0.59) | KCNH2POLA1ALDH1A1NPC1RAB9A | |
| SCHEMBL6284350 | 0.76 | KCNH2 (0.48) | KCNH2POLA1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265873-B1 | 4-OXO-1,4-DIHYDRO-3-CINNOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2003-10-15 | — | — | EP | claimed |