SCHEMBL6670592

SCHEMBL6670592

COC(=O)c1ccccc1COC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
LMNA P02545 4/20 0.61
HSD17B10 Q99714 2/20 0.59
KMT2A Q03164 1/20 0.51
TSHR P16473 1/20 0.50
CFTR P13569 1/20 0.49
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 3/20 0.48
HTT P42858 1/20 0.48
HIF1A Q16665 1/20 0.48
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.47
GAA P10253 1/20 0.46
MAPK8 P45983 1/20 0.46
MAPK9 P45984 1/20 0.46
MAPK10 P53779 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646202 0.88 ALDH1A1 (0.63) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL15413067 0.88 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL7646204 0.86 ALDH1A1 (0.57) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL5914676 0.85 ALDH1A1 (0.55) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL25795046 0.85 ALDH1A1 (0.49) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL6668857 0.85 ALDH1A1 (0.59) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL31618373 0.84 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL15267352 0.84 ALDH1A1 (0.55) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL3150175 0.84 ALDH1A1 (0.62) ALDH1A1LMNAHSD17B10KMT2ATSHR
SCHEMBL6669086 0.84 ALDH1A1 (0.62) ALDH1A1LMNAHSD17B10KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2023-11-23 US disclosed
US-11805776-B2 Compositions and methods for killing insect and non-insect pests THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-11-07 US disclosed
CN-109574965-B Preparation and application of 2- (4-substituent phenyl) -3-formamide benzofuran alkene cyanide compound 上海交通大学 2022-12-30 CN disclosed
WO-2022125885-A1 METHODS FOR KILLING PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2022-06-16 WO disclosed
US-20220183287-A1 METHODS FOR KILLING PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-06-16 US disclosed
WO-2019143506-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2019-07-25 WO disclosed
US-20190216084-A1 Compositions And Methods For Killing Insect And Non-Insect Pests THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2019-07-18 US disclosed
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885HSD17B10 1044/4885
US-11805776-B2 Compositions and methods for killing insect and non-insect pests BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885HSD17B10 1044/4885
US-20190216084-A1 Compositions And Methods For Killing Insect And Non-Insect Pests BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885HSD17B10 1044/4885
US-20220183287-A1 METHODS FOR KILLING PESTS L3MBTL3, AOC3, L3MBTL4 ALDH1A1 884/4885LMNA 3045/4885HSD17B10 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.