Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3924615 | 0.90 | ALDH1A1 (0.32) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL1105692 | 0.76 | HTT (0.58) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| Bromide SCHEMBL3921022 | 0.75 | HTT (0.56) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL14454728 | 0.74 | HTT (0.55) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL13556906 | 0.70 | MAPT (0.50) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL6262227 | 0.70 | KDM4E (0.49) | MEN1KMT2AALDH1A1FABP4KDM4E | |
| SCHEMBL7069862 | 0.69 | ALDH1A1 (0.38) | ALDH1A1POLB | |
| SCHEMBL13464660 | 0.69 | HTT (0.52) | MAPK1KMT2AHTT | |
| SCHEMBL13196417 | 0.69 | MEN1 (0.50) | MEN1APAF1RGS12HSP90AA1MAPK1 | |
| SCHEMBL5536162 | 0.69 | BCHE (0.65) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318177-B1 | Compound, in particular marker-dye, based on polymethines | DYOMICS GMBH (DE) | 2004-09-22 | — | — | EP | disclosed |
| EP-1318177-A2 | Compound, in particular marker-dye, based on polymethines | Dyomics GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |