Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3920896 | 0.92 | KDM4E (0.42) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL7069818 | 0.84 | KDM4E (0.54) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| Bromide SCHEMBL3916333 | 0.83 | KDM4E (0.56) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL1105809 | 0.79 | KDM4E (0.77) | KDM4EPOLBMAPTRECQLKMT2A | |
| Iodide SCHEMBL2057098 | 0.78 | KDM4E (0.75) | KDM4EPOLBALDH1A1MAPTLMNA | |
| Bromide SCHEMBL3915979 | 0.78 | KDM4E (0.80) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL15419914 | 0.77 | KDM4E (0.79) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL7069862 | 0.75 | ALDH1A1 (0.38) | POLBALDH1A1MAPTLMNARAB9A | |
| SCHEMBL16663887 | 0.73 | KDM4E (0.81) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL3183561 | 0.72 | ALDH1A1 (0.34) | ALDH1A1MAPTFABP4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283855-B1 | STABLE NEAR-INFRARED (NIR) MARKER DYES BASED ON BENZOPYRYLIUM-POLYMETHINES | DYOMICS GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6750346-B2 | CHROMENES AS TERMINAL END GROUPS | CARL ZEISS JENA GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1318177-A2 | Compound, in particular marker-dye, based on polymethines | Dyomics GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |
| EP-1283855-A1 | STABLE NEAR-INFRARED (NIR) MARKER DYES BASED ON BENZOPYRYLIUM-POLYMETHINES | Dyomics GmbH (DE) | 2003-02-19 | — | — | EP | disclosed |
| US-20020115862-A1 | Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines | DYOMICS GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
| WO-2001090253-A1 | STABLE NEAR-INFRARED (NIR) MARKER DYES BASED ON BENZOPYRYLIUM-POLYMETHINES | DYOMICS GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115862-A1 | Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines | CYBA, MKI67, CYP3A5 | KDM4E 2204/4885POLB 1529/4885ALDH1A1 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.