Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667141 | 0.90 | CYP1A2 (0.40) | TLR4 | |
| SCHEMBL6666668 | 0.76 | — | — | |
| SCHEMBL6670109 | 0.75 | — | — | |
| SCHEMBL6667494 | 0.75 | — | — | |
| SCHEMBL422994 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL1666552 | 0.75 | TLR4 (0.51) | TLR4 | |
| SCHEMBL8215701 | 0.75 | TLR4 (0.51) | TLR4 | |
| SCHEMBL1666553 | 0.75 | TLR4 (0.51) | TLR4 | |
| SCHEMBL22440632 | 0.74 | TLR4 (0.34) | TLR4 | |
| SCHEMBL6666394 | 0.74 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012148-B1 | MONOACETALS OF BICYCLOHEXYL-4,4-DIONE AND THEIR USE IN PREPARING LIQUID CRYSTALS | ROLIC AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| EP-1012148-A1 | MONOACETALS OF BICYCLOHEXYL-4,4-DIONE AND THEIR USE IN PREPARING LIQUID CRYSTALS | Rolic AG (CH) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999012920-A1 | MONOACETALS OF BICYCLOHEXYL-4,4-DIONE AND THEIR USE IN PREPARING LIQUID CRYSTALS | ROLIC AG (CH) | 1999-03-18 | — | — | WO | disclosed |