SCHEMBL6671399

SCHEMBL6671399

NNc1nc2c(N)ncnc2n1C1OC(CO)C(O)C1O

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSPA8 P11142 7/20 0.82
HSPA5 P11021 3/20 0.82
RXFP1 Q9HBX9 1/20 0.82
SLC28A2 O43868 10/20 0.71
FBP1 P09467 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023025 1.00 HSPA8 (0.82) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL952636 1.00 HSPA8 (0.82) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL952641 1.00 HSPA8 (0.82) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6760673 0.90 HSPA8 (1.00) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6760675 0.90 HSPA8 (1.00) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6685814 0.89 HSPA8 (0.65) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6762443 0.88 FBP1 (0.79) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6762435 0.88 FBP1 (0.79) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL13127208 0.88 HSPA8 (0.80) HSPA8HSPA5RXFP1SLC28A2FBP1
SCHEMBL6763143 0.88 HSPA8 (0.80) HSPA8HSPA5RXFP1SLC28A2FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180355369-A1 Method for Increasing Plant Stress Tolerance and Seed Dormancy THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2018-12-13 US disclosed
WO-2004037159-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM OBETHERAPY BIOTECHNOLOGY (FR) 2004-05-06 WO disclosed