SCHEMBL6671605

SCHEMBL6671605

CC#CC(C)(COCC)NC(=O)C(CC)Oc1cncc(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
P2RX3 P56373 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671901 0.91 HTRA1 (0.32) PKMMAPTKMT2A
SCHEMBL5158389 0.90 PKM (0.35) PKMMAPTKMT2A
SCHEMBL6673612 0.89 PKM (0.33) PKMMAPTKMT2A
SCHEMBL5160452 0.86 PKM (0.35) PKM
SCHEMBL5158909 0.81 HTRA1 (0.32)
SCHEMBL6249581 0.80 TSHR (0.32) PKM
SCHEMBL5161063 0.79 PPARG (0.33)
SCHEMBL5158887 0.78
SCHEMBL6252253 0.78 NPSR1 (0.32) PKM
SCHEMBL5160818 0.77 CHRNB2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456174-A1 PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES Syngenta Limited (GB) 2004-09-15 EP disclosed
WO-2003048128-A1 PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES SYNGENTA LIMITED (GB) 2003-06-12 WO disclosed