Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252988 | 0.91 | HTRA1 (0.31) | ALDH1A1 | |
| SCHEMBL6671901 | 0.89 | HTRA1 (0.32) | PKM | |
| SCHEMBL6253709 | 0.87 | PKM (0.32) | TSHRPKMPOLBGAANPSR1 | |
| SCHEMBL6252253 | 0.86 | NPSR1 (0.32) | PKMNPSR1 | |
| SCHEMBL4616219 | 0.86 | PKM (0.35) | TSHRPKMPOLBGAANPSR1 | |
| SCHEMBL6250808 | 0.81 | POLB (0.34) | TSHRPKMPOLBGAANPSR1 | |
| SCHEMBL6671605 | 0.80 | PKM (0.31) | PKM | |
| SCHEMBL11875470 | 0.79 | POLB (0.38) | TSHRPKMPOLBGAANPSR1 | |
| SCHEMBL4612427 | 0.79 | GRN (0.33) | ALDH1A1 | |
| SCHEMBL5158389 | 0.79 | PKM (0.35) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567479-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048315-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |