Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415762 | 0.83 | TSHR (0.45) | TSHRALDH1A1GLATP53MAPT | |
| Hydrochloric Acid SCHEMBL11299546 | 0.82 | TSHR (0.44) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL26088406 | 0.81 | TSHR (0.47) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL10939839 | 0.79 | TSHR (0.43) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL2398343 | 0.79 | TAAR1 (0.47) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL6648280 | 0.78 | NR1H2 (0.41) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL11308081 | 0.78 | TSHR (0.44) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL317239 | 0.77 | TAAR1 (0.46) | TSHRALDH1A1GLATP53MAPT | |
| Sulfuric Acid SCHEMBL9329973 | 0.76 | TP53 (0.46) | TSHRALDH1A1GLATP53MAPT | |
| SCHEMBL2215314 | 0.75 | TSHR (0.41) | TSHRALDH1A1GLATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474425-A1 | DEAZAPURINES AND USES THEREOF | Eisai Co. Ltd. (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003057696-A1 | DEAZAPURINES AND USES THEREOF | EISAI CO. LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |