Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161436 | 0.89 | RAB9A (0.67) | GAAMAPTRAB9AKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL163829 | 0.86 | GAA (0.64) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL28663846 | 0.86 | GAA (0.56) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL13127250 | 0.82 | MAPT (0.58) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL13107871 | 0.82 | MAPT (0.58) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL20123327 | 0.82 | MAPT (0.81) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL24947672 | 0.81 | APP (0.59) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL13127241 | 0.78 | SAE1 (0.65) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL29113884 | 0.78 | MAPT (0.54) | GAAMAPTRAB9AKDM4ETDP1 | |
| SCHEMBL6374784 | 0.77 | TRPA1 (0.61) | RAB9AKDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174419-B1 | A method for producing an alpha-aminonitrile from a tertiary amine and a cyanide through oxidation with oxygen by using a transition metal catalyst | UNIV OSAKA (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6486340-B2 | Method for producing an α-aminonitrile from a tertiary anime and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-11-26 | — | — | US | disclosed |
| US-20020042534-A1 | Method for producing an alpha-aminonitrile from a tertiary anime and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-04-11 | — | — | US | disclosed |
| EP-1174419-A1 | A method for producing an alpha-aminonitrile from a tertiary amine and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-01-23 | — | — | EP | disclosed |