Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161436 | 0.87 | RAB9A (0.67) | APPNPC1RAB9AGAAMAPT | |
| Hydrochloric Acid SCHEMBL163829 | 0.84 | GAA (0.64) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL674764 | 0.84 | APP (0.77) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL8422557 | 0.84 | APP (0.77) | APPRAB9AMAPTKDM4ETHRB | |
| SCHEMBL10300057 | 0.84 | APP (0.77) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL9715639 | 0.82 | APP (0.74) | APPNPC1RAB9AGAAMAPT | |
| Acetonitrile SCHEMBL6671920 | 0.81 | GAA (0.54) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL13127250 | 0.80 | MAPT (0.58) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL20123327 | 0.80 | MAPT (0.81) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL13107871 | 0.80 | MAPT (0.58) | APPNPC1RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037175-A1 | HIGH REFRACTIVE INDEX ORGANIC SOLID CRYSTAL WITH CONTROLLED SURFACE ROUGHNESS | FACEBOOK TECHNOLOGIES, LLC | 2023-02-02 | — | — | US | disclosed |