Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998425 | 0.95 | PDE4B (0.59) | ALDH1A1TSHRPDE4BFDPSTTR | |
| SCHEMBL3359792 | 0.92 | PDE4B (0.49) | ALDH1A1TSHRPDE4BFDPSPTPN1 | |
| SCHEMBL3594038 | 0.91 | PDE4B (0.64) | ALDH1A1TSHRPDE4BFDPSTTR | |
| SCHEMBL24366316 | 0.88 | PDE4B (0.55) | ALDH1A1TSHRPDE4BPTPN1KDM4E | |
| SCHEMBL24588569 | 0.87 | PDE4B (0.51) | ALDH1A1TSHRPDE4BPTPN1HPGD | |
| SCHEMBL5863923 | 0.85 | PDE4B (0.47) | ALDH1A1TSHRPDE4BPTPN1ALDH1A3 | |
| SCHEMBL3362581 | 0.84 | PDE4B (0.45) | ALDH1A1TSHRPDE4BPTPN1ALDH1A3 | |
| SCHEMBL24367560 | 0.83 | KDM4E (0.60) | ALDH1A1PDE4BPTPN1HPGDKDM4E | |
| SCHEMBL31428576 | 0.83 | FDPS (0.61) | ALDH1A1TSHRFDPSHPGDTDP1 | |
| SCHEMBL9013036 | 0.83 | KDM4E (0.60) | ALDH1A1PDE4BPTPN1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11844846-B2 | Styrylbenzothiazole derivatives and uses in imaging methods | EMORY UNIVERSITY (US) | 2023-12-19 | — | — | US | disclosed |
| CN-108516929-B | 2-methylene- (3-methoxy-4-hydroxy) -benzyl-1-indanone analogue and application thereof | 温州医科大学 | 2021-06-18 | — | — | CN | disclosed |
| EP-3793619-A1 | STYRYLBENZOTHIAZOLE DERIVATIVES AND USES IN IMAGING | Emory University (US) | 2021-03-24 | — | — | EP | disclosed |
| CN-112105393-A | Styrylbenzothiazole derivatives and use in imaging | 爱默蕾大学 | 2020-12-18 | — | — | CN | disclosed |
| EP-3564204-A1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | The University of Tokyo (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-3045445-B1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | UNIV TOKYO (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-2606021-B1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | UNIV TOKYO (JP) | 2019-07-31 | — | — | EP | disclosed |
| EP-3045445-A1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | THE UNIVERSITY OF TOKYO (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-9359279-B2 | Treatment of cancer, inflammatory disease, and autoimmune disease | ALLIANZ PHARMASCIENCE LTD. (TW) | 2016-06-07 | — | — | US | disclosed |
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC UNM (US) | 2016-02-11 | — | — | US | disclosed |
| WO-2012024282-A2 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | SHIH CHARLES C-Y (US) | 2012-02-23 | — | — | WO | disclosed |
| US-7728043-B2 | Methods for treatment of beta-amyloid protein-induced ocular disease | KIM DARRICK S H L | 2010-06-01 | — | — | US | disclosed |
| WO-2010046926-A2 | NOVEL STILBENE ANALOGS | APTUIT LAURUS PVT LTD (IN) | 2010-04-29 | — | — | WO | disclosed |
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-06-07 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | KIM DARRICK S H | 2007-01-04 | — | — | US | disclosed |
| EP-0705817-A1 | New cannamide derivatives and their use as allergy inhibitors | TSUMURA & CO. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | APP, BACE1, GSAP | ALDH1A1 2716/4885TSHR 4196/4885PDE4B 3947/4885 |
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | ALDH1A1 670/4885TSHR 4278/4885PDE4B 3587/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | ALDH1A1 670/4885TSHR 4278/4885PDE4B 3587/4885 |
| US-11844846-B2 | Styrylbenzothiazole derivatives and uses in imaging methods | SNCA, NLN, SMN1; SMN2 | ALDH1A1 1535/4885TSHR 3678/4885PDE4B 1161/4885 |
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | DHX15, DHX35, DUT | ALDH1A1 2503/4885TSHR 2263/4885PDE4B 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.