Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141105 | 0.85 | TSHR (0.32) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL3195038 | 0.81 | GABRA1 (0.37) | SLC6A2CYP3A4CYP2D6GABRA1GABRB2 | |
| SCHEMBL5488086 | 0.76 | TSHR (0.37) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL28936286 | 0.76 | MAPT (0.37) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8750534 | 0.75 | GABRA1 (0.39) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL6546540 | 0.74 | GABRA1 (0.42) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL29657207 | 0.74 | GABRA1 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4GABRA1 | |
| SCHEMBL545484 | 0.74 | GABRA1 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4GABRA1 | |
| SCHEMBL4089214 | 0.74 | TSHR (0.33) | SLC6A2SLC6A4SLC6A3GABRA1GABRB2 | |
| SCHEMBL10721566 | 0.73 | GABRA1 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969007-B1 | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | DOW CORNING ASIA LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6054602-A | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | DOW CORNING ASIA, LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0969007-A2 | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | Dow Corning Asia, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |