Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839515 | 0.85 | TSHR (0.33) | TSHRSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3627333 | 0.78 | TSHR (0.59) | TSHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL7614292 | 0.77 | ESR1 (0.42) | TSHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL9078971 | 0.77 | CYSLTR2 (0.36) | NPSR1ALDH1A1 | |
| SCHEMBL5486163 | 0.77 | ADRB2 (0.43) | TSHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL9080668 | 0.77 | — | — | |
| SCHEMBL9078908 | 0.77 | — | — | |
| SCHEMBL6672069 | 0.76 | SLC6A2 (0.35) | TSHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5494557 | 0.76 | HTT (0.42) | TSHRCYP3A4HTTALDH1A1 | |
| SCHEMBL5488485 | 0.76 | CYP3A4 (0.41) | TSHRSLC6A2SLC6A4CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |