Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738818 | 0.83 | PRMT5 (0.40) | PRMT5WDR77ADKENPP1 | |
| SCHEMBL29407693 | 0.83 | PRMT5 (0.40) | PRMT5WDR77ADKENPP1 | |
| SCHEMBL19993789 | 0.80 | ADK (0.45) | ADORA2AADORA1PRMT5WDR77ADK | |
| SCHEMBL21367268 | 0.79 | PRMT5 (0.47) | ADORA2AADORA1PRMT5WDR77ADK | |
| SCHEMBL2293269 | 0.75 | ADORA2A (0.66) | USP2PNPTSHREDNRAHTR2A | |
| SCHEMBL13067510 | 0.75 | PRMT5 (0.39) | SRCADORA2APRMT5WDR77ADK | |
| SCHEMBL24236880 | 0.75 | ADK (0.46) | TSHRHSD17B10ADORA2AADORA1PRMT5 | |
| SCHEMBL30336240 | 0.74 | NSD3 (0.40) | ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL30335860 | 0.74 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL12151781 | 0.73 | ADORA2A (0.53) | ADORA2AADORA1PRMT5WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |