Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691735 | 0.79 | OPRM1 (0.56) | OPRM1OPRD1OPRK1ACACBACACA | |
| SCHEMBL3895438 | 0.77 | OPRM1 (0.64) | OPRM1OPRD1OPRK1P4HTM | |
| SCHEMBL27741121 | 0.77 | KMT2A (0.45) | LTB4RLTB4R2ALOX5SLC6A2SLC6A3 | |
| SCHEMBL29757291 | 0.72 | OPRM1 (0.64) | OPRM1OPRD1OPRK1P4HTM | |
| SCHEMBL27897920 | 0.72 | ATM (0.47) | KCNH2 | |
| SCHEMBL3771658 | 0.72 | OPRM1 (1.00) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL28384505 | 0.71 | NPC1 (0.46) | SLC6A2 | |
| SCHEMBL23488365 | 0.71 | P4HTM (0.77) | OPRM1OPRD1OPRK1P4HTMFFAR1 | |
| SCHEMBL12018652 | 0.70 | OPRM1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL7330265 | 0.70 | LTB4R (0.48) | LTB4RLTB4R2FFAR1FFAR4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026305-A9 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2004-05-13 | — | — | WO | disclosed |