Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363128 | 0.84 | LMNA (0.46) | KDM4EPOLBALDH1A1LMNATDP1 | |
| SCHEMBL1173073 | 0.81 | LMNA (0.40) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28077001 | 0.79 | KDM4E (0.50) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5661958 | 0.76 | KDM4E (0.57) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| Acrylonitrile SCHEMBL22207118 | 0.75 | MCL1 (0.43) | KDM4EKMT2APOLBALDH1A1LMNA | |
| SCHEMBL9799758 | 0.75 | EP300 (0.36) | ALDH1A1GRIK1CYP2D6CYP2C19 | |
| SCHEMBL9799762 | 0.75 | EP300 (0.36) | ALDH1A1GRIK1CYP2D6CYP2C19 | |
| SCHEMBL374959 | 0.74 | KDM4E (0.68) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11419752 | 0.74 | TDP1 (0.40) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9289108 | 0.73 | KDM4E (0.63) | KDM4EMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464119-A2 | BIOCOMPATIBLE MEMBRANES OF BLOCK COPOLYMERS AND FUEL CELLS PRODUCED THEREWITH | Powerzyme, Inc. (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003050897-A2 | BIOCOMPATIBLE MEMBRANES OF BLOCK COPOLYMERS AND FUEL CELLS PRODUCED THEREWITH | POWERZYME, INC. (US) | 2003-06-19 | — | — | WO | disclosed |