SCHEMBL374959

SCHEMBL374959

CCCCOC(=O)C(C)=CC=Cc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.68
POLB P06746 1/20 0.57
TDP1 Q9NUW8 3/20 0.56
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 7/20 0.50
LMNA P02545 5/20 0.50
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.45
TSHR P16473 2/20 0.45
HPGD P15428 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9289108 0.96 KDM4E (0.63) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL6545140 0.95 KDM4E (0.62) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL1998845 0.95 KDM4E (0.62) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL8945396 0.95 KDM4E (0.62) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL10395020 0.90 POLB (0.56) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL10395019 0.90 POLB (0.56) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL5661958 0.89 KDM4E (0.57) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL4914902 0.89 KDM4E (0.55) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL4243868 0.87 KDM4E (0.60) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL5406162 0.86 POLB (0.53) KDM4EPOLBTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025062180-A1 SYSTEMS, METHODS, AND COMPOSITIONS FOR UPCYCLING POLYESTERS 9449710 CANADA INC. (CA) 2025-03-27 WO claimed
US-10507174-B2 Skin care compositions ROHM AND HAAS COMPANY (US) 2019-12-17 US claimed
CN-1124969-A Styrenic polymer foam with comonomer content DOW CHEMICAL CO (US) 1996-06-19 CN claimed
US-5489497-A COMPRISED OF RESIN, MAGNETITE COATED WITH PHOSPHATE TITANIUM COMPOUND, WAX, CHARGE ADDITIVE, SILICA AND METAL OXIDES; ELECTROSTATIC IMAGING XEROX CORPORATION (US) 1996-02-06 US claimed
US-5326662-A Passivated toner compositions and processes thereof XEROX CORPORATION (US) 1994-07-05 US claimed
US-5278018-A Magnetic toner compositions containing charge enhancing additive particles XEROX CORPORATION (US) 1994-01-11 US claimed
US-4937163-A Imaging member and processes thereof XEROX CORPORATION (US) 1990-06-26 US claimed
US-4920023-A TREATING COATED CARRIER PARTICLES WITH METAL SALTS OR METAL SALTS OF FATTY ACIDS, MIXING WITH TONER COMPOSITION XEROX CORPORATION (US) 1990-04-24 US claimed
US-4737434-A USING PARTICLES OF TWO DIFFERENT POLYMERS XEROX CORPORATION (US) 1988-04-12 US claimed
US-4565765-A Process of developing electrostatic latent images comprised of rotating magnets contained in stationary shell and synthetic carrier XEROX CORPORATION (US) 1986-01-21 US claimed
EP-0145300-A1 Electrostatic development apparatus XEROX CORPORATION (US) 1985-06-19 EP claimed
US-4464452-A NEGATIVE CHARGE ENHANCER XEROX CORPORATION (US) 1984-08-07 US claimed
US-4298672-A ELECTROGRAPHY XEROX CORPORATION (US) 1981-11-03 US claimed
US-4287284-A AND A DEVELOPER OF BUTYL METHACRYLATE-STYRENE RESIN OR BUTADIENE-STYRENE RESIN WITH CARBON BLACK, AND A CARRIER OF POLYVINYLIDENE FLUORIDE COATED STEEL XEROX CORPORATION (US) 1981-09-01 US claimed
EP-0005952-A1 Electrostatographic toner containing an alkyl pyridinium compound and imaging method XEROX CORPORATION (US) 1979-12-12 EP claimed
JP-58118655-A None JP disclosed
US-12458931-B2 Methods for preparing microcapillary carbon molecular sieve membranes DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-04 US disclosed
US-4299898-A Positively charged toners containing quaternary ammonium salts attached to acrylate polymers XEROX CORPORATION (US) 1981-11-10 US disclosed
US-4187329-A Electrophotographic developing process and compositions for use therein INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1980-02-05 US disclosed
EP-0005334-A1 Electrophotographic toner composition XEROX CORPORATION (US) 1979-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10507174-B2 Skin care compositions CUTA, MMS19, SOD1 KDM4E 3609/4885POLB 156/4885TDP1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.