Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639001 | 0.95 | MAOA (0.50) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL6388482 | 0.93 | MAOA (0.48) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL27488335 | 0.93 | MAOA (0.48) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL2374703 | 0.91 | MAOA (0.54) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL11365074 | 0.84 | MAOA (0.48) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL28259694 | 0.83 | OPRL1 (0.41) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL28161193 | 0.81 | MAOA (0.48) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL13757097 | 0.81 | TSHR (0.46) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL11474711 | 0.79 | MEN1 (0.47) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL23542798 | 0.78 | ESR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | claimed |
| CN-109313397-A | The manufacturing method of laminated body, the manufacturing method of semiconductor element and laminated body | 富士胶片株式会社 | 2019-02-05 | — | — | CN | disclosed |
| EP-1465862-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | SmithKline Beecham Corporation (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003062192-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |