Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388482 | 1.00 | MAOA (0.48) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL5639001 | 0.98 | MAOA (0.50) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL6672640 | 0.93 | MAOA (0.50) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL28259694 | 0.89 | OPRL1 (0.41) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL2374703 | 0.89 | MAOA (0.54) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL11365074 | 0.83 | MAOA (0.48) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL11817033 | 0.81 | ACAT2 (0.39) | KMT2A | |
| SCHEMBL28161193 | 0.79 | MAOA (0.48) | MAOAMAOBOPRM1OPRK1OPRL1 | |
| SCHEMBL18114513 | 0.79 | OPRM1 (0.42) | MAOAMAOBOPRM1OPRL1SLC6A3 | |
| SCHEMBL13757097 | 0.79 | TSHR (0.46) | MAOAMAOBOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1939909-A | Control of arthropods in animals | AVENTIS CROPSCIENCE SA (FR) | 2007-04-04 | — | — | CN | disclosed |
| CN-1402713-A | Controlling arthropods in animals | AVENTIS CROPSCIENCE SA (FR) | 2003-03-12 | — | — | CN | disclosed |
| CN-1161034-A | Substituted cycloalkylamino and cycloalkoxy heterocycles, process for preparing the same and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-01 | — | — | CN | disclosed |