SCHEMBL6388482

SCHEMBL6388482

CC1(Cc2ccccc2)CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
OPRM1 P35372 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
SLC6A4 P31645 3/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
ALDH1A1 P00352 1/20 0.40
ADRB2 P07550 1/20 0.40
HTT P42858 1/20 0.40
ELANE P08246 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488335 1.00 MAOA (0.48) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL5639001 0.98 MAOA (0.50) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL6672640 0.93 MAOA (0.50) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL28259694 0.89 OPRL1 (0.41) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL2374703 0.89 MAOA (0.54) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL11365074 0.83 MAOA (0.48) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL11817033 0.81 ACAT2 (0.39) KMT2A
SCHEMBL28161193 0.79 MAOA (0.48) MAOAMAOBOPRM1OPRK1OPRL1
SCHEMBL18114513 0.79 OPRM1 (0.42) MAOAMAOBOPRM1OPRL1SLC6A3
SCHEMBL13757097 0.79 TSHR (0.46) MAOAMAOBOPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4302350-A2 LIQUID CARBON-NEUTRAL ENERGY FACILITY SYSTEM The Claire Technologies Corporation (US) 2024-01-10 EP claimed
US-11848468-B2 Liquid carbon-neutral energy facility system CLAIRE Technologies (US) 2023-12-19 US claimed
EP-4225694-A1 CARBON-NEUTRAL PROCESS FOR GENERATING ELECTRICITY The Claire Technologies Corporation (US) 2023-08-16 EP claimed
WO-2022203824-A2 LIQUID CARBON-NEUTRAL ENERGY FACILITY SYSTEM The Claire Technologies Corporation (US) 2022-09-29 WO claimed
US-20220285714-A1 LIQUID CARBON-NEUTRAL ENERGY FACILITY SYSTEM The Claire Technologies Corporation (US) 2022-09-08 US claimed
WO-2022076219-A1 CARBON-NEUTRAL PROCESS FOR GENERATING ELECTRICITY The Claire Technologies Corporation (US) 2022-04-14 WO claimed
US-11236028-B2 Production and use of 3,4′ and 4,4′-dimethylbiphenyl isomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-01 US claimed
US-20210053890-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers EXXONMOBIL CHEMICAL PATENTS INC. 2021-02-25 US claimed
US-20200325096-A1 Oxidation of Methyl-substituted Biphenyl Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2020-10-15 US claimed
US-10710945-B2 Aromatic compositions and methods for obtaining them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
WO-2014159101-A1 METHYL-SUBSTITUTED BIPHENYL COMPOUNDS, THEIR PRODUCTION AND THEIR USE IN THE MANUFACTURE OF PLASTICIZERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-02 WO claimed
WO-2014159100-A1 (METHYLCYCLOHEXYL)TOLUENE ISOMER MIXTURES, THEIR PRODUCTION AND THEIR USE IN THE MANUFACTURE OF PLASTICIZERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-02 WO claimed
US-20140275605-A1 (Methylcyclohexyl)Toluene Isomer Mixtures,Their Production and Their Use in the Manufacture of Plasticizers EXXONMOBIL CHEMICAL PATENTS INC. 2014-09-18 US claimed
US-20140275606-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers EXXONMOBIL CHEMICAL PATENTS INC. 2014-09-18 US claimed
US-20140275607-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers EXXONMOBIL CHEMICAL PATENTS INC. 2014-09-18 US claimed
US-20140275609-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers EXXONMOBIL CHEMICAL PATENTS INC. 2014-09-18 US claimed
US-20050215433-A1 Aromatic fluid as agricultural solvent EXXONMOBIL CHEMICAL PATENTS INC. 2005-09-29 US claimed
US-20050054819-A1 Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors SMITHKLINE BEECHAM CORPORATION 2005-03-10 US claimed
EP-1465862-A1 CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS SmithKline Beecham Corporation (US) 2004-10-13 EP claimed
WO-2003062192-A1 CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-07-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275605-A1 (Methylcyclohexyl)Toluene Isomer Mixtures,Their Production and Their Use in the Manufacture of Plasticizers DDT, CYP3A4, TERT MAOA 2360/4885MAOB 2678/4885OPRM1 413/4885
US-20050054819-A1 Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors CTSK, CTSS, CTSE MAOA 2083/4885MAOB 2350/4885OPRM1 4338/4885
US-20140275606-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers BMI1, DNMT3B, DNMT1 MAOA 465/4885MAOB 194/4885OPRM1 2645/4885
US-20200325096-A1 Oxidation of Methyl-substituted Biphenyl Compounds CYP1B1, CYP1A1, CYP4B1 MAOA 238/4885MAOB 79/4885OPRM1 357/4885
US-20140275607-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers DNMT3B, DNMT1, BMI1 MAOA 488/4885MAOB 219/4885OPRM1 1880/4885
US-20210053890-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers BMP4, DBF4, EIF4B MAOA 2449/4885MAOB 952/4885OPRM1 3097/4885
US-10710945-B2 Aromatic compositions and methods for obtaining them AHR, ARNT, TDO2 MAOA 842/4885MAOB 570/4885OPRM1 4139/4885
US-20050215433-A1 Aromatic fluid as agricultural solvent DDT, AHR, ALB MAOA 762/4885MAOB 952/4885OPRM1 4523/4885
US-11236028-B2 Production and use of 3,4′ and 4,4′-dimethylbiphenyl isomers BMP4, DBF4, EIF4B MAOA 2459/4885MAOB 945/4885OPRM1 3137/4885
US-20140275609-A1 Methyl-Substituted Biphenyl Compounds, Their Production and Their Use in the Manufacture of Plasticizers DDT, HPD, AHR MAOA 388/4885MAOB 295/4885OPRM1 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.