Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408883 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBPTPN1 | |
| SCHEMBL9408798 | 0.82 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL4979055 | 0.81 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBCRHBP | |
| SCHEMBL508460 | 0.81 | NPC1 (0.62) | NPC1RAB9ALMNAPOLBCYP2C9 | |
| SCHEMBL9408769 | 0.81 | NPC1 (0.51) | NPC1RAB9ALMNAPOLBCYP2C9 | |
| SCHEMBL9408845 | 0.81 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBPTPN1 | |
| Hydrochloric Acid SCHEMBL8372133 | 0.80 | NPC1 (0.61) | NPC1RAB9ALMNAPOLBCYP2C9 | |
| SCHEMBL7752841 | 0.79 | CYP3A4 (0.41) | NPC1RAB9ALMNAPOLBCRHBP | |
| SCHEMBL6672691 | 0.79 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBCRHBP | |
| SCHEMBL9408768 | 0.78 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |