Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650011 | 0.94 | DRD4 (0.40) | DRD4KDM4ETAAR1LMNACYP1A2 | |
| SCHEMBL6651627 | 0.85 | KDM4E (0.35) | DRD4KDM4EUTS2RCHRNB2CHRNA4 | |
| SCHEMBL6649431 | 0.82 | DRD4 (0.37) | DRD4DRD2DRD1DRD5TAAR1 | |
| SCHEMBL6651166 | 0.80 | KDM4E (0.38) | DRD4KDM4EDRD2DRD1DRD5 | |
| SCHEMBL6653862 | 0.80 | CYP1A2 (0.35) | DRD4KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL6650118 | 0.79 | DRD4 (0.35) | DRD4DRD2DRD1DRD5TAAR1 | |
| SCHEMBL6651100 | 0.78 | HRH3 (0.38) | DRD4KDM4ETAAR1LMNACYP1A2 | |
| SCHEMBL6675930 | 0.76 | TRPM5 (0.50) | DRD4KDM4EDRD2DRD1DRD5 | |
| SCHEMBL6654434 | 0.75 | DRD4 (0.37) | DRD4KDM4EDRD1LMNACYP1A2 | |
| SCHEMBL6653570 | 0.73 | HSP90AA1 (0.46) | DRD4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |