Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | BRD2 | P25440 | 4/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819087 | 0.87 | PDE1A (0.39) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL22772903 | 0.74 | PDE1A (0.44) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL20754852 | 0.72 | BTK (0.49) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL6674661 | 0.71 | NPC1 (0.35) | RAB9ANPC1KDM4EMAPTPDE2A | |
| SCHEMBL20406251 | 0.70 | BTK (0.53) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL6676477 | 0.69 | UGCG (0.36) | MAPT | |
| SCHEMBL22940967 | 0.68 | RAB9A (0.47) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL15674574 | 0.67 | DHODH (0.47) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL2713912 | 0.67 | S100A4 (0.49) | RAB9ANPC1PDE1APDE1BPDE1C | |
| SCHEMBL6918490 | 0.67 | CRHR1 (0.33) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035564-A1 | PYRIDINE DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004035563-A1 | 3-HETEROCYCLYLPYRIDINE DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-29 | — | — | WO | disclosed |