Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350115 | 0.86 | BAZ1A (0.65) | EPHX2RAB9AMEN1HTTKMT2A | |
| SCHEMBL4346187 | 0.85 | EPHX1 (0.63) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28356482 | 0.85 | EPHX1 (0.74) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2752048 | 0.83 | EPHX2 (0.71) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20365330 | 0.79 | KMT2A (0.67) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8391687 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12196184 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3886168 | 0.76 | EPHX2 (0.58) | EPHX2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL23736048 | 0.74 | EPHX2 (0.75) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5598039 | 0.74 | EPHX2 (0.75) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |