Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | MTOR | P42345 | 3/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672789 | 0.86 | EPHX1 (0.60) | BAZ1AEPHX2TRPV1MEN1KMT2A | |
| SCHEMBL26697260 | 0.86 | CA12 (0.64) | BAZ1AEPHX2TRPV1MEN1KMT2A | |
| SCHEMBL6760901 | 0.85 | EPHX2 (0.56) | BAZ1AEPHX2TRPV1MEN1KMT2A | |
| SCHEMBL1463622 | 0.85 | TRPV1 (0.70) | BAZ1ATRPV1MEN1KMT2AMAPT | |
| SCHEMBL18031166 | 0.84 | EPHX2 (0.85) | BAZ1AEPHX2TRPV1MEN1KMT2A | |
| SCHEMBL5595005 | 0.82 | CXCR1 (0.70) | BAZ1AEPHX2TRPV1MEN1KMT2A | |
| SCHEMBL5595251 | 0.82 | RAB9A (0.66) | BAZ1AEPHX2MEN1KMT2AMAPT | |
| SCHEMBL4350776 | 0.82 | KMT2A (0.49) | BAZ1ATRPV1MEN1KMT2AMAPT | |
| SCHEMBL4342071 | 0.82 | EPHX2 (0.68) | EPHX2MEN1KMT2AMAPTHTT | |
| SCHEMBL5595105 | 0.81 | CXCR1 (0.70) | EPHX2TRPV1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065760-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES AND USE THEREOF | JERINI AG (DE) | 2011-03-17 | — | — | US | claimed |
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |
| US-20070054904-A1 | Phenol derivatives and their use as rotamase inhibitors | JERINI AG (DE) | 2007-03-08 | — | — | US | claimed |
| CN-1701061-A | Novel compounds for inhibiting rotamase enzymes and uses thereof | JERINI AG (DE) | 2005-11-23 | — | — | CN | claimed |
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065760-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES AND USE THEREOF | NR1I3, NR1D1, NR1D2 | BAZ1A 1985/4885EPHX2 769/4885TRPV1 2328/4885 |
| US-20070054904-A1 | Phenol derivatives and their use as rotamase inhibitors | NR1I3, NR1D1, NR1D2 | BAZ1A 1267/4885EPHX2 627/4885TRPV1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.