Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.47 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673030 | 0.89 | MAPT (0.53) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL6576793 | 0.82 | AKR1C2 (0.56) | RAB9ANPC1AKR1C2ALDH1A1HTT | |
| SCHEMBL19436969 | 0.74 | MAPT (0.52) | MAPTRAB9ASMN1; SMN2GAALMNA | |
| SCHEMBL19436968 | 0.74 | MAPT (0.52) | MAPTRAB9ASMN1; SMN2GAALMNA | |
| SCHEMBL141710 | 0.71 | MAPT (0.63) | MAPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL8474824 | 0.71 | CA12 (0.55) | RAB9ASMN1; SMN2NPC1TP53AKR1C2 | |
| SCHEMBL8474827 | 0.71 | CA12 (0.55) | RAB9ASMN1; SMN2NPC1TP53AKR1C2 | |
| SCHEMBL19436960 | 0.70 | AKR1C2 (0.56) | MAPTRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL19436961 | 0.70 | AKR1C2 (0.56) | MAPTRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL12632097 | 0.69 | HSD17B10 (0.54) | MAPTRAB9ANPC1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458695-A1 | PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003057679-A9 | PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE (US) | 2004-02-26 | — | — | WO | disclosed |
| WO-2003057679-A1 | PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |