Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25708575 | 0.82 | CNR2 (0.34) | — | |
| SCHEMBL12166768 | 0.81 | SHBG (0.33) | LMNACYP2C9 | |
| SCHEMBL17972923 | 0.81 | SHBG (0.33) | LMNACYP2C9 | |
| SCHEMBL27250636 | 0.80 | — | — | |
| SCHEMBL15498977 | 0.80 | — | — | |
| Ethane SCHEMBL6508257 | 0.79 | GBA1 (0.33) | GBA1SILMNACYP2C9 | |
| SCHEMBL5247885 | 0.78 | TRPA1 (0.32) | GBA1 | |
| SCHEMBL21350163 | 0.78 | TRPA1 (0.32) | GBA1 | |
| SCHEMBL12166485 | 0.77 | CA1 (0.43) | — | |
| SCHEMBL2345485 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003066007-A1 | HAIR CARE COMPOSITIONS CONTAINING POLYSILOXANES | DOW CORNING CORPORATION (US) | 2003-08-14 | — | — | WO | claimed |
| US-6255429-B1 | FIBER TREATMENT COMPOSITIONS PROVIDING GOOD HAND, RESISTANCE TO YELLOWING, AND HYDROPHILICITY | DOW CORNING CORPORATION | 2001-07-03 | — | — | US | claimed |
| US-9359719-B2 | Self-crosslinkable polysiloxane-modified polyhydroxy polyurethane resin, process for producing said resin, resin material comprising said resin, and artificial leather produced utilizing said resin | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20140024274-A1 | SELF-CROSSLINKABLE POLYSILOXANE-MODIFIED POLYHYDROXY POLYURETHANE RESIN, PROCESS FOR PRODUCING SAID RESIN, RESIN MATERIAL COMPRISING SAID RESIN, AND ARTIFICIAL LEATHER PRODUCED UTILIZING SAID RESIN | UKIMA CHEMICALS & COLOR MFG. CO., LTD. (JP) | 2014-01-23 | — | — | US | disclosed |
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |
| EP-1081272-B1 | Fiber treatment composition containing amine, polyol, amide-functional siloxanes | DOW CORNING (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-1081271-B1 | Fiber treatment composition containing amine, polyol, functional siloxanes | DOW CORNING (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003066007-A1 | HAIR CARE COMPOSITIONS CONTAINING POLYSILOXANES | DOW CORNING CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |
| US-6255429-B1 | FIBER TREATMENT COMPOSITIONS PROVIDING GOOD HAND, RESISTANCE TO YELLOWING, AND HYDROPHILICITY | DOW CORNING CORPORATION | 2001-07-03 | — | — | US | disclosed |
| EP-1081272-A1 | Fiber treatment composition containing amine, polyol, amide-functional siloxanes | DOW CORNING CORPORATION (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1081271-A1 | Fiber treatment composition containing amine, polyol, functional siloxanes | DOW CORNING CORPORATION (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6171515-B1 | Fiber treatment composition containing amine-, polyol-, functional siloxanes | DOW CORNING CORPORATION | 2001-01-09 | — | — | US | disclosed |
| US-6136215-A | FOR IMPARTING NATURAL AND SYNTHETIC TEXTILE FILBERS WITH HYDROPILICITY AND YELLOWING RESISTANCE AND HAND(FEEL) | DOW CORNING CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |