Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191308 | 0.81 | LMNA (0.32) | LMNACYP2C9 | |
| SCHEMBL6672824 | 0.79 | GBA1 (0.34) | GBA1SILMNACYP2C9 | |
| SCHEMBL12166493 | 0.79 | SHBG (0.33) | LMNACYP2C9 | |
| SCHEMBL14115900 | 0.79 | SHBG (0.33) | LMNACYP2C9 | |
| SCHEMBL17972921 | 0.79 | SHBG (0.33) | LMNACYP2C9 | |
| SCHEMBL15498977 | 0.78 | — | — | |
| SCHEMBL27250636 | 0.78 | — | — | |
| SCHEMBL19558077 | 0.77 | CNR2 (0.44) | LMNACYP2C9 | |
| SCHEMBL300849 | 0.76 | TRPA1 (0.32) | GBA1 | |
| SCHEMBL12166771 | 0.76 | CA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009799-A1 | Cyclohexyl derivatives as selective estrogen receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009799-A1 | Cyclohexyl derivatives as selective estrogen receptor modulators | ESR2, GPER1, ESR1 | GBA1 4449/4885SI 4626/4885LMNA 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.