Trolamine

Trolamine

SCHEMBL43636

C=C(C)C(=O)O.C=C(C)C(=O)O.OCCN(CCO)CCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
ALOX15 P16050 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 2/20 0.33
TGFBR1 P36897 1/20 0.33
HIF1A Q16665 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
SCN1A P35498 1/20 0.31
KMT2A Q03164 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
EYA2 O00167 1/20 0.31
APP P05067 1/20 0.31
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL345855 1.00 MAPT (0.37) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL44442 1.00 MAPT (0.37) MAPTALOX15KDM4ESMN1; SMN2TDP1
Methacrylic Acid SCHEMBL9222623 0.91 CA12 (0.35) MAPTALOX15KDM4ESMN1; SMN2HIF1A
Methacrylic Acid SCHEMBL43870 0.89 CYP1A2 (0.44) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Diethylaminoethanol SCHEMBL11695020 0.89 CYP1A2 (0.39) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Methacrylic Acid SCHEMBL344337 0.89 CYP1A2 (0.44) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Methacrylic Acid SCHEMBL9138338 0.88 KDM5A (0.41) KDM4EMEN1LMNACYP3A4CYP2D6
Trolamine SCHEMBL238201 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL29400146 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL28327104 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552300-A Method for realizing anti-caking of acrylic resin powder by chemical doping method 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
CN-119552299-A Method for realizing anti-caking of acrylic resin powder 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
US-4543371-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1985-09-24 US claimed
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US claimed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US disclosed
US-4338419-A REDUCING IRRITATION FROW WEARING CONTACT LENSES SYNTEX (U.S.A.) INC. (US) 1982-07-06 US disclosed
EP-0032905-A4 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. FOLEY WILLIAM M JUN 1981-08-27 EP disclosed
EP-0032905-A1 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS FOLEY, Jr., William M. (US) 1981-08-05 EP disclosed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US disclosed
WO-1980002840-A1 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS FOLEY W 1980-12-24 WO disclosed
US-4180308-A Contact lens SYNTEX (USA) INC. (US) 1979-12-25 US disclosed
US-4056496-A ACRYLIC CORNEAL SCIENCES, INC. (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 MAPT 1040/4885ALOX15 153/4885KDM4E 2952/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A MAPT 344/4885ALOX15 1864/4885KDM4E 2118/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 MAPT 2163/4885ALOX15 549/4885KDM4E 1444/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885ALOX15 2690/4885KDM4E 2312/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 MAPT 999/4885ALOX15 2215/4885KDM4E 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.