Trolamine

Trolamine

SCHEMBL345855

C=C(C)C(=O)O.OCCN(CCO)CCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
ALOX15 P16050 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 2/20 0.33
TGFBR1 P36897 1/20 0.33
HIF1A Q16665 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
SCN1A P35498 1/20 0.31
KMT2A Q03164 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
EYA2 O00167 1/20 0.31
APP P05067 1/20 0.31
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL43636 1.00 MAPT (0.37) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL44442 1.00 MAPT (0.37) MAPTALOX15KDM4ESMN1; SMN2TDP1
Methacrylic Acid SCHEMBL9222623 0.91 CA12 (0.35) MAPTALOX15KDM4ESMN1; SMN2HIF1A
Methacrylic Acid SCHEMBL43870 0.89 CYP1A2 (0.44) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Diethylaminoethanol SCHEMBL11695020 0.89 CYP1A2 (0.39) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Methacrylic Acid SCHEMBL344337 0.89 CYP1A2 (0.44) MAPTALOX15KDM4ESMN1; SMN2TGFBR1
Methacrylic Acid SCHEMBL9138338 0.88 KDM5A (0.41) KDM4EMEN1LMNACYP3A4CYP2D6
Trolamine SCHEMBL238201 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL29400146 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1
Trolamine SCHEMBL28327104 0.84 FFAR3 (0.44) MAPTALOX15KDM4ESMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552299-A Method for realizing anti-caking of acrylic resin powder 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
CN-119552300-A Method for realizing anti-caking of acrylic resin powder by chemical doping method 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
CN-118344032-A Auxiliary cementing material for concrete and preparation method and application thereof 中建西部建设西南有限公司 2024-07-16 CN claimed
CN-106565122-B Mcromolecular grinding aid and its preparation method and application 同济大学 2018-12-18 CN claimed
CN-106565122-A Polymeric grinding aid, and preparation method and application thereof 同济大学 2017-04-19 CN claimed
EP-0470008-B1 Polymerisable compositions and use of these compositions for the sealing of underground media RHONE POULENC CHIMIE (FR) 1994-10-12 EP claimed
EP-0263647-B1 PVA gel SHINETSU CHEMICAL CO (JP) 1994-01-05 EP claimed
US-5250645-A Methoxypolyalkoxyethyl methacrylate or acrylate, an initiator, polymerization accelerator and water RHONE-POULENC CHIMIE (FR) 1993-10-05 US claimed
US-4844744-A Liquid, phosphate-free single phase degreasing compositions HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-07-04 US claimed
US-4788242-A Polyvinyl alcohol-based reversibly hydrated gel, highly water-absorptive resin and method for the preparation thereof SHIN-ESTU CHEMICAL CO., LTD. (JP) 1988-11-29 US claimed
US-4351922-A ADDITION-CONDENSATION POLYMERS FROM UNSATURATED CARBOXY ACIDS, SULFONIC ACIDS, AMIDES, OR NITRILES AND GLYCIDOL-MODIFIED POLYOXYETHYLENE GLYCOL SHOWA DENKO KABUSHIKI KAISHA (JP) 1982-09-28 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-6316528-B1 AS UNDERFILLING SEALING RESIN WHICH ENABLES A SEMICONDUCTOR DEVICE TO BE SECURELY CONNECTED TO CIRCUIT BOARD LOCTITE (R&D) LIMITED (IE) 2001-11-13 US disclosed
US-6274389-B1 Mounting structure and mounting process from semiconductor devices LOCTITE (R&D) LTD. (IE) 2001-08-14 US disclosed
CN-1277834-A Cementation composite and prepn. method therefor KURARAY CO (JP) 2000-12-27 CN disclosed
US-5250645-A Methoxypolyalkoxyethyl methacrylate or acrylate, an initiator, polymerization accelerator and water RHONE-POULENC CHIMIE (FR) 1993-10-05 US disclosed
US-4351922-A ADDITION-CONDENSATION POLYMERS FROM UNSATURATED CARBOXY ACIDS, SULFONIC ACIDS, AMIDES, OR NITRILES AND GLYCIDOL-MODIFIED POLYOXYETHYLENE GLYCOL SHOWA DENKO KABUSHIKI KAISHA (JP) 1982-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A MAPT 344/4885ALOX15 1864/4885KDM4E 2118/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885ALOX15 2690/4885KDM4E 2312/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 MAPT 999/4885ALOX15 2215/4885KDM4E 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.