SCHEMBL667301

SCHEMBL667301

COC=C(C#N)C(=O)OC(C)C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
PTP4A3 O75365 1/20 0.45
PTP4A2 Q12974 1/20 0.45
PTP4A1 Q93096 1/20 0.45
MAPT P10636 1/20 0.42
TP53 P04637 2/20 0.39
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.33
CYP2C9 P11712 1/20 0.33
ADRA1A P35348 1/20 0.32
PDE4D Q08499 1/20 0.32
IDE P14735 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653026 1.00 ALDH1A1 (0.46) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21037252 0.84 ALDH1A1 (0.50) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL27853457 0.84 ALDH1A1 (0.50) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL11651550 0.80 ALDH1A1 (0.43) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL11651547 0.80 ALDH1A1 (0.43) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL11653074 0.79 ADORA2A (0.41) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL5555667 0.79 ADORA2A (0.41) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL24089780 0.78 ALDH1A1 (0.47) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL7547841 0.77 ALDH1A1 (0.46) ALDH1A1PTP4A1MAPTTP53HPGD
SCHEMBL7547838 0.77 ALDH1A1 (0.46) ALDH1A1PTP4A1MAPTTP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390105-A1 METHODS AND DEVICES FOR CONTROLLED DELIVERY POINTILLIST GLOBAL MACRO SERIES OF POINTILLIST PARTNERS LLC 2023-12-07 US claimed
CN-113874459-B Flexible photocurable cyanoacrylate compositions 汉高股份有限及两合公司 2023-07-04 CN disclosed
US-9402762-B2 Methods and devices for conduit occlusion FEMASYS INC. 2016-08-02 US disclosed
US-9220880-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2015-12-29 US disclosed
US-20150068531-A1 METHODS AND DEVICES FOR CONDUIT OCCLUSION FEMASYS INC. (US) 2015-03-12 US disclosed
US-8726906-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2014-05-20 US disclosed
US-20130220335-A1 Methods and Devices for Conduit Occlusion FEMASYS INC. (US) 2013-08-29 US disclosed
US-20130225977-A1 Methods and Devices for Delivery of Compositions to Conduits FEMASYS INC. (US) 2013-08-29 US disclosed
US-8336552-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2012-12-25 US disclosed
US-8324193-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2012-12-04 US disclosed
US-20120042880-A1 Methods and Devices for Conduit Occlusion FEMASYS INC. (US) 2012-02-23 US disclosed
US-20120046260-A1 Methods and Devices for Delivery of Compositions to Conduits FEMASYS INC. (US) 2012-02-23 US disclosed
US-8052669-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2011-11-08 US disclosed
US-8048101-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2011-11-01 US disclosed
US-20100056626-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2010-03-04 US disclosed
EP-2081567-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES Metis S.r.l. (IT) 2009-07-29 EP disclosed
US-20090024155-A1 Methods and Devices for Conduit Occlusion FEMASYS, INC. 2009-01-22 US disclosed
US-20090024108-A1 Methods and Devices for Delivery of Compositions to Conduits FEMASYS, INC. 2009-01-22 US disclosed
WO-2008059541-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2008-05-22 WO disclosed
US-4104049-A Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed